Interaction Report for Atorvastatin | |||
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NAME: Atorvastatin |
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ALSO INDEXED AS: Lipitor |
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INTRODUCTION:
Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor, is used to lower cholesterol and triglycerides in patients with hypercholesterolemia and mixed dyslipidemia and in the treatment of homozygous familial hypercholesterolemia. Atorvastatin has a unique structure, long half-life, and hepatic selectivity, explaining its greater LDL-lowering potency compared to other HMG-CoA reductase inhibitors. |
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INTERACTIONS WITH DIETARY SUPPLEMENTS:
Vitamin A:Adverse effects noted. Lipitor increases vitamin A levels Vitamin B3:Ingestion of large amounts of niacin along with lovastatin (a drug closely related to atorvastatin) or with atorvastatin itself may cause muscle disorders (myopathy) that can become serious (rhabdomyolysis). Individuals taking atorvastatin should consult their physician before taking niacin Vitamin E:Atorvastatin could play a role in decreasing the antioxidant activity of vitamin E. |
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